Additional Benefits of CBD

In a previous article, “CBD: What Does the Research Say,” we examined some of the scientifically-backed benefits of CBD supplementation, including CBD’s pain relieving, mood supporting, acne preventing, and neuroprotective effects. I recommend reading that article before this one because there is prerequisite knowledge in that article concerning the body’s endocannabinoid system and the differences between CBD and THC.

Because CBD is a rather new compound, most of the studies have been conducted recently, and there will be more and more information discovered. In this article, we will examine the research investigating CBD’s benefits for people with multiple sclerosis, potential benefits of CBD in cancer treatment, and the cardiovascular benefits of CBD. *

Multiple Sclerosis

The National Multiple Sclerosis Society estimates that nearly one million people in the United States are living with multiple sclerosis (MS), which is up dramatically from the 1981 estimate of four hundred thousand [1]. The disease itself is a severely disabling neurological condition and has a wide range of associated conditions which fluctuate from total vision loss and a reduced sense of taste to tremors and muscle spasms [2]. While there is no cure for MS, there are several pharmaceutical medications that can help decrease the severity and frequency of the symptoms of the disease.

Since MS is a neurologically oriented disease, and CBD seems to affect the neurological system, researchers are investigating the possible therapeutic benefits of CBD for people living with MS.

In a 2017 review that investigated the neurological-supporting aspects of CBD, researchers reviewed the available literature studying CBD therapy in a wide variety of neurological disorders, such as Parkinson’s disease (PD), Alzheimer’s disease (AD), and multiple sclerosis (MS), to name a few. Overall, the researchers stated that there is a large amount of pre-clinical evidence that shown CBD can produce beneficial effects in MS patients and called for more clinical examinations [3].

Additionally, in a 2018 review, researchers investigated the available research studying CBD and MS specifically. The researchers found several studies, including randomized and controlled trials, that found there was satisfactory evidence that CBD may be useful for symptoms of pain and spasticity in patients that have MS [4].

Researchers in 2015 investigated the benefits of CBD in the experimental multiple sclerosis model and found that CBD, singly, possesses an anti-apoptotic power against the neurodegenerative processes that underly MS development [5]. Another supplementary study came to the same conclusion, noting CBD anti-inflammatory effects [6].

Further, a 2005 study investigated the effects of CBD in MS patients while sleeping and found the compound reduced neurological pain and improved sleep quality [7].

These are only five of the many studies that have investigated the potential therapeutic benefits of CBD in patients with MS; there are many more [8-14].

Cancer Treatment

There is a lot of research that has explored the potential beneficial effects of CBD for cancer patients. Not only to cancer patients have to battle the disease itself, but the patient also experiences a wide variety of negative symptoms of the disease and its treatment. These symptoms can include nausea, vomiting, or pain, and CBD is beneficial in these aspects, especially when combined with THC.

For example, a 2009 randomized, placebo-controlled, parallel-group study found that when CBD was combined with THC, it produced pain relief in patients with advanced cancer pain not fully relieved by potent opioids [15].

Other studies have found that CBD may help to relieve chemotherapy-induced nausea and vomiting, which are two distinguished side-effects of chemotherapy treatment [16] [17].

Even though there are drugs that are designed to help with cancer-related pain, nausea, and vomiting, they can be ineffective, and CBD may be an invaluable solution.

Studies have also investigated CBD’s anti-cancer properties.

For example, several studies have found that CBD has anti-tumor properties [18-20].  

Further, a 2018 study found that CBD was a novel inhibitor for exosome and microvesicle (EMV) release in cancer [21]. The EMV process is associated with various pathologies, including cancer, and increased EMV activity is associated with chemoresistance. When EMV activity is decreased, cancer cells are more susceptible to treatment. This study found CBD was an effective EMV inhibitor in types of prostate cancer, liver cancer, and breast cancer [21].

Another study, published in 2011, found that concentrated CBD induced cell death in breast cancer cells [22], and a study published in 2077 found that CBD decreased the spread of breast cancer cells in mice [23].

However, although many studies show promise regarding CBD as an alternative or in addition to traditional cancer treatment, most of these studies are either in vitro or animal studies. Therefore, it is crucial this compound undergoes further research before any resolute conclusion can be made.

Cardiovascular Health

Scientists have researched CBD’s benefits regarding cardiovascular health and found numerous benefits regarding the heart and circulatory system. High blood pressure can lead to a wide array of difficulties, such as cardiovascular disease, stroke, heart attack, or metabolic syndrome [24]. Therefore, it is essential to have healthy blood pressure parameters.

In a 2017, researchers investigated whether CBD supplementation could reduce blood pressure in humans in a randomized, placebo-controlled, double-blind, crossover study [25]. The researchers found that CBD reduced systolic [upper measurement] blood pressure six mmHg, even with an increased heart rate due to the test. Further, during the stress test in the study, which usually is when blood pressure rises, blood pressure still stayed at a decreased level. This study shows CBD can reduce resting blood pressure and blood pressure during a stress test better than a placebo [25].

A handful of further studies have investigated the benefits of CBD in specific circumstances.  

For example, a 2015 study noted that CBD therapy might be beneficial for patients recovering from a heart attack or myocardial infarction [26].

Moreover, a 2015 study found that CBD causes vasorelaxation [reduction in vascular tension] of human mesenteric arteries [27]; a 2010 study found that CBD decreases cardiac dysfunction, oxidative stress, and inflammation in patients with diabetic cardiomyopathy [28]; a 2018 animal study observed the effects of CBD might be useful in treating arterial plaquing and decreasing the chance of myocardial infarction and cardiac arrhythmia [29]. Withal, though, these studies have not been conducted in humans, so it essential for human studies to be undertaken before any reliable conclusions are drawn.

Conclusion

Currently, CBD continues to show promise in a variety of circumstances. In this article, we examined CBD benefits as they relate to multiple sclerosis, cancer treatment, and cardiovascular health. Also, it essential to note some of the benefits of CBD are drawn from test tube and animal studies and may not reflect benefits in humans. However, as more studies are administered, that will be judged.

If you are interested in trying a CBD supplement, check out Healthmasters’ Organic CBD Oil. If you have any questions about Healthmasters’ Organic CBD Oil, please feel free to call our office at 800.726.1834.

 

References:

[1] https://www.nationalmssociety.org/About-the-Society/MS-Prevalence/MS-Prevalence-FAQ

[2] https://msfocus.org/Get-Educated/Symptoms-of-MS.aspx

[3] https://www.ncbi.nlm.nih.gov/pubmed/28412918

[4] https://www.ncbi.nlm.nih.gov/pubmed/29442178

[5] https://www.ncbi.nlm.nih.gov/pubmed/26744883                

[6] https://www.ncbi.nlm.nih.gov/pubmed/23851307

[7] https://www.ncbi.nlm.nih.gov/pubmed/16186518

[8] https://www.ncbi.nlm.nih.gov/pubmed/27160523

[9] https://www.ncbi.nlm.nih.gov/pubmed/29633480

[10] https://www.ncbi.nlm.nih.gov/pubmed/22739983

[11] https://www.ncbi.nlm.nih.gov/pubmed/19228180

[12] https://www.ncbi.nlm.nih.gov/pubmed/17355549

[13] https://www.ncbi.nlm.nih.gov/pubmed/25857324

[14] https://www.ncbi.nlm.nih.gov/pubmed/21094240

[15] https://www.ncbi.nlm.nih.gov/pubmed/19896326

[16] https://www.ncbi.nlm.nih.gov/pubmed/16983116

[17] https://www.ncbi.nlm.nih.gov/pubmed/28780725

[18] https://www.ncbi.nlm.nih.gov/pubmed/16616335

[19] https://www.ncbi.nlm.nih.gov/pubmed/12514108

[20] https://www.ncbi.nlm.nih.gov/pubmed/30019449

[21] https://www.ncbi.nlm.nih.gov/pubmed/30150937

[22] https://www.ncbi.nlm.nih.gov/pubmed/21566064

[23] https://www.ncbi.nlm.nih.gov/pubmed/18025276

[24] https://www.ncbi.nlm.nih.gov/pubmed/23536128

[25] https://www.ncbi.nlm.nih.gov/pubmed/28614793

[26] https://www.ncbi.nlm.nih.gov/pubmed/26065843

[27] https://www.ncbi.nlm.nih.gov/pubmed/26092099

[28] https://www.ncbi.nlm.nih.gov/pubmed/21144973

[29] https://www.ncbi.nlm.nih.gov/pubmed/30464888

​*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

* This article is for informational purposes only. By providing the information herein, Healthmasters and its associates are not diagnosing, treating, curing, mitigating or preventing any type of disease or medical condition. Before beginning any type of natural, integrative, or conventional treatment or regime, it is advisable to seek the advice of a licensed healthcare professional.