Super Potent E

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SKU: 4038
$29.99

 

Applications for Health Improvement

  • Offers antioxidant protection for cell membranes and lipids
  • Supports healthy a healthy inflammation response
  • Supports neuroprotection and cognitive health
  • Supports cardiovascular, nervous and reproduction systems
  • Supports liver health
  • Provides mixed tocopherols and tocotrienols for comprehensive vitamin E nutrition

 

60 Softgels

 

While numerous studies show that vitamin E suppresses free radicals, there is evidence that many commercial vitamin E supplements do not provide adequate antioxidant protection. This is because most vitamin E supplements consist primarily of alpha tocopherol. Recent studies indicate that a lot more than alpha tocopherol is needed to protect against degenerative disease.

Vitamin E, in its natural form, comprises eight different compounds: alpha-, beta-, gamma-, and delta-tocopherols and alpha-, beta-, gamma-, and delta-tocotrienols. Both tocopherols and tocotrienols are important to human health. Known as the “master antioxidant,” vitamin E has the ability to attenuate oxidative stress, and its antioxidant-related effects on various organs and systems have been the focus of vast research. Though the vast majority of research has been on alpha-tocopherol, recent mechanistic studies indicate that other isomers of vitamin E, such as gamma- and delta tocopherols and tocotrienols, have superior antioxidant and cell signaling properties that offer greater health benefits [1,2].

Tocotrienols: Studies have demonstrated that tocotrienols have superior antioxidant activity compared to tocopherols. Tocotrienols also exhibit biological activities related to neuroprotection, radioprotection, cell-life regulation, cytokine modulation, and lipid metabolism that are not shared by tocopherols [3-5].

EVNol SupraBio™ is a natural, full-spectrum tocopherol and tocotrienol complex extracted and concentrated from the red palm fruits of sustainable plantations in Peninsular Malaysia. This vitamin E complex also contains minute amounts of other phytonutrients such as plant squalene, phytosterols, coenzyme Q10, and mixed carotenoids that are naturally extracted together with tocotrienols. This patented formula contains a precise mixture of oil and approved food emulsifiers at optimum ratio and processing that self-emulsifies in the gastrointestinal tract to facilitate and provide a rapid and consistent absorption of tocotrienols into the plasma, independent of dietary fat or food intake.

EVNol SupraBio™ is the only tocotrienol/tocopherol complex in the market that has been the subject of an actual human tissue distribution study. In that study, it was demonstrated that orally supplemented tocotrienols from EVNol SupraBio are absorbed into plasma and delivered and accumulated in vital organs, including the brain [6]. EVNol SupraBio™ is a heavily researched tocopherol/tocotrienol product that has been scientifically substantiated with human clinical studies on brain health, liver support, beauty, and cardiovascular health [7-11].

 

References

  1. Jiang Q, Yin X, Lill MA, et al. Long-chain carboxychromanols, metabolites of vitamin E, are potent inhibitors of cyclooxygenases. Proc Natl Acad Sci U S A. 2008 Dec 23;105(51):20464-69. [PMID: 19074288]
  2. Ahsan H, Ahad A, Iqbal J, et al. Pharmacological potential of tocotrienols: a review. Nutr Metab (Lond). 2014 Nov 12;11(1):52. [PMID: 25435896]
  3. Ahsan H, Ahad A, Iqbal J, et al. Pharmacological potential of tocotrienols: a review. Nutr Metab (Lond). 2014 Nov 12;11(1):52. [PMID: 25435896]
  4. Osakada F, Hashino A, Kume T, et al. Alpha-tocotrienol provides the most potent neuroprotection among vitamin E analogs on cultured striatal neurons. Neuropharmacol. 2004 Nov;47(6):904-15. [PMID: 15527824]
  5. Fu JY, Che HL, Tan DM, et al. Bioavailability of tocotrienols: evidence in human studies. Nutr Metab (Lond). 2014 Jan 13;11(1):5. [PMID: 24410975]
  6. Patel V, Rink C, Gordillo GM, et al. Oral tocotrienols are transported to human tissues and delay the progression of the model for end-stage liver disease score in patients. J Nutr. 2012 Mar;142(3):513-19. [PMID: 22298568]
  7. Patel V, Rink C, Gordillo GM, et al. Oral tocotrienols are transported to human tissues and delay the progression of the model for end-stage liver disease score in patients. J Nutr. 2012 Mar;142(3):513-19. [PMID: 22298568]
  8. Gopalan Y, Shuaib IL, Magosso E, et al. Clinical investigation of the protective effects of palm vitamin E tocotrienols on brain white matter. Stroke. 2014 May;45(5):1422-8. [PMID: 24699052]
  9. Thendiono J, Arguillas M. The effect of vitamin E (mixed tocotrienol) on the liver stiffness measurement measured by transient elastography (fibroscan) among NAFLD patients. Presented at: 23rd Conference Meeting of the Asian Pacific Association for the Study of Liver; June 6-10, 2013; Singapore. http://www.excelvite.com/wp-content/ uploads/2015/04/EFFECT1.pdf. Accessed June 6, 2016.
  10. Rasool AH, Rahman AR, Yuen KH, et al. Arterial compliance and vitamin E blood levels with a self emulsifying preparation of tocotrienol rich vitamin E. Arch Pharm Res. 2008 Sep;31(9):1212-17. [PMID: 18806966]
  11. Beoy LA, Woei WJ, Hay YK. Effects of tocotrienol supplementation on hair growth in human volunteers. Trop Life Sci Res. 2010 Dec;21(2):91-99. [PMID: 24575202]

 

 

Supplement Facts (made with non-GMO ingredients)

 

  Amount Per Serving % Daily Value

Vitamin E (as d-alpha tocopherol)

50 IU 167%

EVNOL SupraBio™ Bio-Enhanced Natural Full Spectrum Tocotrienol/Tocopherol Complex

164.5 mg **

Total Mixed Tocotrienols

25 mg **

d-Gamma Tocotrienol

11.5 mg **

d-Alpha Tocotrienol

7.4 mg **

d-Delta Tocotrienol

4.1 mg **

d-Beta Tocotrienol

822.5 **

Total Mixed Tocotrienol

125 mg **

Typical Composition:

   

d-Gamma Tocopherol

75 mg **

d-Delta Tocopherol

30 mg **

d-Alpha Tocopherol

17.5 mg **

d-Beta Tocopherol

2.5 mg **